Retrospective study
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Positive FIT? Don’t Skip the Colonoscopy!
Among 45,598 adults with a positive fecal immunochemical test, 17,727 had a colonoscopy within a year. After matching patients on recorded characteristics, colonoscopy completion was associated with lower…
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Tumour bacteria may mark a higher risk of recurrence
In 740 people with stage I to III colorectal cancer, tumours containing Fusobacterium species were associated with shorter recurrence-free survival after surgery, with an adjusted hazard ratio of…
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Older surgical patients had 66.2% five-year recurrence-free survival
In this English national cohort, patients over 75 selected for curative colorectal cancer surgery had lower five-year recurrence-free survival than younger patients, largely alongside higher death from both…
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Severe immune toxicity linked to 48.6% response in MSI-H cancers
In this 1,175-patient retrospective study, people who developed severe immune-related side effects had a higher recorded response rate to immunotherapy. The association is hypothesis-generating, not proof that toxicity…
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84.8% two-year survival after deceased-donor transplant in 35 selected patients
In this six-centre retrospective cohort, 35 people with unresectable colorectal liver metastases received deceased-donor liver transplants. Survival after transplant was high at two years, but the study had…
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Colonoscopy linked to 25% lower CRC hazard at ages 75–79
In a Korean retrospective cohort, adults aged 75 to 79 who had colonoscopy had a lower observed rate of newly diagnosed colorectal cancer than matched adults who did…