Supplements and repurposed drugs
-
Platelet drugs were linked to lower colorectal cancer mortality
In 334,882 Swedish people with atherosclerotic cardiovascular disease, P2Y12 inhibitor use was not linked to fewer new colorectal cancers, but longer use was associated with lower colorectal cancer…
-
Higher-dose vitamin D did not slow metastatic colorectal cancer
Among 455 people starting treatment for metastatic colorectal cancer, median progression-free survival was 11.8 months with high-dose vitamin D3 and 10.3 months with standard-dose vitamin D3, a difference…
-
Nutrition drinks were linked to fewer chemotherapy changes after surgery
In a 157-person randomised trial, chemotherapy modifications occurred in 17.5% of patients given oral nutritional supplements plus dietary advice, versus 35.1% given dietary advice alone. Five-year all-cause mortality…
-
Aspirin reduced DFS events 39% in PIK3CA exon 9/20 tumours
A meta-analysis of three randomised trials found fewer disease-free survival events with adjuvant aspirin in colorectal tumours carrying PIK3CA exon 9 or 20 mutations. The ASCOLT trial’s own…