Supplements and repurposed drugs
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Higher-dose vitamin D did not slow metastatic colorectal cancer
Among 455 people starting treatment for metastatic colorectal cancer, median progression-free survival was 11.8 months with high-dose vitamin D3 and 10.3 months with standard-dose vitamin D3, a difference…
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Nutrition drinks were linked to fewer chemotherapy changes after surgery
In a 157-person randomised trial, chemotherapy modifications occurred in 17.5% of patients given oral nutritional supplements plus dietary advice, versus 35.1% given dietary advice alone. Five-year all-cause mortality…
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Aspirin reduced DFS events 39% in PIK3CA exon 9/20 tumours
A meta-analysis of three randomised trials found fewer disease-free survival events with adjuvant aspirin in colorectal tumours carrying PIK3CA exon 9 or 20 mutations. The ASCOLT trial’s own…