The CRC Blueprint

My scientific approach to my own cancer – shared with you.

Phase 3

AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer

Phase 3 · randomised · 560 people · 2 sites in China · Recruiting now

August 7, 2026
SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC

Phase 3 · randomised · 204 people · 1 site in China · Recruiting now

August 7, 2026
A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC

Phase 3 · randomised · 280 people · 1 site in China · Recruiting now

August 7, 2026
ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer

Phase 3 · randomised · 103 people · 25 sites in Netherlands · Recruiting now

August 7, 2026
Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon Cancer

Phase 3 · randomised · 1,083 people · 1 site in Spain · Recruiting now

August 7, 2026
Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery

Phase 3 · randomised · 131 people · 4 sites in 2 countries · Recruiting now

August 7, 2026
Study on Aspirin Versus Placebo in Resected Colon Cancer With PI3K Mutation Stage III or II High Risk

Phase 3 · randomised · 264 people · 1 site in France · Running, not taking new patients

August 7, 2026
De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer

Phase 3 · randomised · 408 people · 1 site in France · Opening soon

August 7, 2026
Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer

Phase 3 · randomised · 236 people · 3 sites in South Korea · Recruiting now

August 7, 2026
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer

Phase 3 · randomised · 960 people · 1 site in Puerto Rico · Recruiting now

August 7, 2026