treatment toxicity
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Severe immune toxicity linked to 48.6% response in MSI-H cancers
In this 1,175-patient retrospective study, people who developed severe immune-related side effects had a higher recorded response rate to immunotherapy. The association is hypothesis-generating, not proof that toxicity…
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Intensified preoperative treatment improved 3-year disease-free survival by 8.8 points
In a 458-patient randomised trial of high-risk locally advanced rectal cancer, a chemotherapy-intensified total neoadjuvant therapy regimen produced higher 3-year disease-free survival than conventional chemoradiotherapy. It also caused…