The CRC Blueprint

My scientific approach to my own cancer – shared with you.

Recruiting now

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

Phase 2 · randomised · 170 people · 14 sites in 4 countries · Recruiting now

August 7, 2026
Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

Phase 2 · randomised · 86 people · 6 sites in United States · Recruiting now

August 7, 2026
Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer

Phase 3 · randomised · 236 people · 3 sites in South Korea · Recruiting now

August 7, 2026
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Phase 2 · randomised · 482 people · 14 sites in 5 countries · Recruiting now

August 7, 2026
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Phase 2 · randomised · 390 people · 59 sites in 14 countries · Recruiting now

August 7, 2026
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer

Phase 3 · randomised · 960 people · 1 site in Puerto Rico · Recruiting now

August 7, 2026
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 · randomised · 800 people · 285 sites in 17 countries · Recruiting now

August 7, 2026
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Phase 2 · 225 people · 53 sites in 11 countries · Recruiting now

August 7, 2026
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Phase 2 · randomised · 144 people · 39 sites in 6 countries · Recruiting now

August 7, 2026
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Phase 3 · randomised · 250 people · 113 sites in 2 countries · Recruiting now

August 7, 2026