Rectal
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Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial
Phase 2 · randomised · 130 people · 1 site in China · Recruiting now
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Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
Phase 3 · randomised · 140 people · 5 sites in Switzerland · Recruiting now
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Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer
Phase 3 · randomised · 582 people · 1 site in China · Recruiting now
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Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer
Phase 3 · randomised · 1,660 people · 1 site in France · Recruiting now
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Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer
Phase 3 · randomised · 188 people · 14 sites in France · Recruiting now
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SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC
Phase 3 · randomised · 204 people · 1 site in China · Recruiting now
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Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3
Phase 2 · 100 people · 11 sites in United States · Recruiting now
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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Phase 2 · 140 people · 48 sites in 8 countries · Recruiting now
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ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer
Phase 3 · randomised · 103 people · 25 sites in Netherlands · Recruiting now