The CRC Blueprint

My scientific approach to my own cancer – shared with you.

Any genotype

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Phase 3 · randomised · 408 people · 62 sites in United States · Recruiting now

August 7, 2026
Bevacizumab-based Chemotherapy Adapted to Bevacizumab Pharmacokinetics in 1st-line Treatment

Phase 3 · randomised · 244 people · 4 sites in France · Recruiting now

August 7, 2026
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Phase 2 · randomised · 482 people · 14 sites in 5 countries · Recruiting now

August 7, 2026
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Phase 2 · randomised · 390 people · 59 sites in 14 countries · Recruiting now

August 7, 2026
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 · randomised · 800 people · 285 sites in 17 countries · Recruiting now

August 7, 2026
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Phase 2 · 225 people · 53 sites in 11 countries · Recruiting now

August 7, 2026
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Phase 2 · randomised · 144 people · 39 sites in 6 countries · Recruiting now

August 7, 2026
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

Phase 3 · randomised · 700 people · 35 sites in 8 countries · Recruiting now

August 7, 2026
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer

Phase 3 · randomised · 1,020 people · 21 sites in 6 countries · Recruiting now

August 7, 2026
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

Phase 3 · randomised · 364 people · 187 sites in 2 countries · Recruiting now

August 7, 2026