The CRC Blueprint

My scientific approach to my own cancer – shared with you.

France

Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer

Phase 3 · randomised · 1,660 people · 1 site in France · Recruiting now

August 7, 2026
Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer

Phase 3 · randomised · 188 people · 14 sites in France · Recruiting now

August 7, 2026
A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Phase 2 · randomised · 108 people · 59 sites in 15 countries · Running, not taking new patients

August 7, 2026
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Phase 2 · randomised · 768 people · 105 sites in 10 countries · Recruiting now

August 7, 2026
Safety of HRX215 in Patients After Minor and Major Liver Resection

Phase 2 · randomised · 80 people · 12 sites in 5 countries · Recruiting now

August 7, 2026
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Phase 2 · 560 people · 54 sites in 7 countries · Recruiting now

August 7, 2026
Study on Aspirin Versus Placebo in Resected Colon Cancer With PI3K Mutation Stage III or II High Risk

Phase 3 · randomised · 264 people · 1 site in France · Running, not taking new patients

August 7, 2026
De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer

Phase 3 · randomised · 408 people · 1 site in France · Opening soon

August 7, 2026
Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

Phase 2 · randomised · 302 people · 109 sites in 22 countries · Running, not taking new patients

August 7, 2026
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Phase 2 · randomised · 80 people · 76 sites in 12 countries · Recruiting now

August 7, 2026