Treatments being tested
Clinical trials open to people with bowel cancer
Every trial here is a live record from ClinicalTrials.gov, the public registry every trial must be listed on before it starts. Statuses are re-checked against the registry every day or two, because a list that says a closed trial is recruiting is worse than no list at all.
Listing a trial is not a recommendation, and this site has no connection to any of them. Whether a trial is right for you, and whether you would be eligible, is a conversation for your own oncology team.
What these filters mean
Genotype
These are the things that make a tumour unusual, so leave them alone unless one of them is yours. Nothing selected shows every trial. Wild-type and pMMR are the ordinary results and have no button of their own: they would match almost everybody, so they would narrow nothing. Selecting a mutation drops the trials that need the ordinary result instead â which is right, because those are the ones you could not join.
Which KRAS
Only relevant if your tumour is KRAS mutated. Your report will name the exact change, such as G12C or G12D; some newer drugs are built for one specific change and no other.
Each trial is tagged by reading its own eligibility criteria automatically, to make the list searchable. The tags summarise what the criteria mention — they are not a decision about whether you qualify, and where a tag and the criteria disagree, the criteria are right.
95 trials
Recruiting nowPhase 1
T Cell Receptor T Cells for Advanced KRAS G12V-mutant Non-small Cell Lung Cancer, Pancreas Cancer, Colon Cancer
Recruiting nowPhase 1
This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors
Recruiting nowPhase 1
EMB-01 in Combination With Chemotherapy for Unresectable or Metastatic Colorectal Cancer
Recruiting nowPhase 1
A Phase 1 Study of DEM301 in Participants With Metastatic Colorectal Cancer
Recruiting nowNot phased
SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC
Recruiting nowPhase 1
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
Running, not taking new patientsPhase 1
A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
Recruiting nowNot phased
Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations
Running, not taking new patientsPhase 1
Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer
Recruiting nowNot phased
Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype
Running, not taking new patientsPhase 1
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Recruiting nowPhase 1
LDRT Combined With Immunochemotherapy for Colorectal Cancer With Liver Metastasis
Recruiting nowNot phased
Prehabilitation in High-risk Oncologic Surgery
Recruiting nowPhase 1
A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
Recruiting nowPhase 1
A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor